Cytomegalovirus Immune Globulin Intravenous Injection
Your doctor has ordered cytomegalovirus immune globulin intravenous (CMV-IGIV) to boost your body's natural response to infection after a kidney transplant. The drug will be added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 2 to 4 hours one time every 2 to 4 weeks for up to 16 weeks after the kidney transplant. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how you respond to the medication.
Before administering CMV-IGIV,
- tell your doctor and pharmacist if you are allergic to any drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antibiotics and vitamins.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking CMV-IGIV, call your doctor.
- if you have had a vaccine for measles, mumps, or rubella in the last 3 months, tell your doctor before using CMV-IGIV.
Before you administer CMV-IGIV, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
It is important that you use your medication exactly as directed. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.
CMV-IGIV may cause side effects. Tell your health care provider if any of these symptoms are severe or do not go away:
- joint or muscle pain
- general feeling of discomfort
- leg cramps
- pain at the injection site
If you experience any of the following symptoms, call your health care provider immediately:
- chest tightness
- unusual tiredness or weakness
- redness of face
- upset stomach
- fast or pounding heartbeat
- troubled breathing
- bluish coloring of lips or nailbeds
- burning sensation in the head
- faintness and lightheadedness
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at Web Site] or by phone [1-800-332-1088].
- CMV-IGIV is often given in the hospital but can be given at home. If you take this drug at home, your health care provider probably will give you a 1-day supply of CMV-IGIV at a time. You probably will be told to store your medication in the refrigerator.
- Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature.
- Alternatively, your health care provider may provide you with directions to prepare each dose. CMV-IGIV should be used within 6 hours after mixing.
- Do not allow CMV-IGIV to freeze.
Store your medication only as directed. Make sure you understand what you need to store your medication properly.
Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
If you are receiving CMV-IGIV in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Last Reviewed: September 1, 2010.