Trimebutine
The following information is an educational aid only. It is not intended as a medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

Trimebutine
(trye me BYOO teen)

Canadian Brand Names
Apo-Trimebutine®; Modulon®

Mexican Brand Names
Debridat; Libertrim

Pharmacologic Category
5-HT3 Receptor Antagonist

Reasons not to take this medicine
• If you have an allergy to trimebutine or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

What is this medicine used for?
• This medicine is used to treat irritable bowel syndrome.

• This medicine is used to treat bowel obstruction after surgery.

How does it work?
• Trimebutine acts on the bowel to stimulate movement and decrease irritability.

How is it best taken?
• Take this medicine 30 minutes before meals.

What do I do if I miss a dose? (does not apply to patients in the hospital)
• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

What are the precautions when taking this medicine?
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions. These include sedatives, tranquilizers, mood stabilizers, antihistamines, and other pain medicine.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?
• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Headache.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Diarrhea.

• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

What should I monitor?
• Change in condition being treated. Is it better, worse, or about the same?

• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.

• Follow up with healthcare provider.

Reasons to call healthcare provider immediately
• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Severe dizziness or passing out.

• Significant change in thinking clearly and logically.

• Severe headache.

• Feeling extremely tired or weak.

• Severe constipation.

• Severe diarrhea.

• Any rash.

• No improvement in condition or feeling worse.

How should I store this medicine?
• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

General statements
• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• You may report side effects to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2008-01-16 14:21:57.0

Modified: 2009-02-19 16:01:04.0

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