Gastric Ulcer
En Español (Spanish Version)


Definition
A gastric ulcer is a sore in the lining of your stomach. Ulcers can be treated. A small percentage of them may be cancerous. See your doctor if you think you may have a gastric ulcer.

Gastric Ulcer

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Causes
Most gastric ulcers are caused by a bacterial infection. It is most often Helicobacter pylori . An ulcer may also be caused by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Risk Factors
Some factors thought to increase the risk of a gastric ulcer are:
  • Gender: male
  • Older age (the incidence of gastric ulcer peaks at age 50)
  • Regular use of pain medications
  • Smoking
  • High levels of stress
  • Lower socioeconomic status
  • Alcohol use
  • Acid reflux
  • Gastritis
  • Cirrhosis
  • Chronic kidney failure
  • Chronic obstructive pulmonary disease (COPD)
  • Use of steroid medications

Symptoms
Symptoms include:
  • Abdominal pain that may:
    • Wake you at night
    • Be relieved by antacids or milk
    • Occur 2-3 hours after a meal
    • Be worse when you don't eat
  • Nausea
  • Abdominal indigestion
  • Vomiting, especially blood
  • Blood in stools or black, tarry stools
  • Unintentional weight loss
  • Fatigue
  • Burning pain in the gut that feels like a dull ache and comes and goes, often starts 2-3 hours after a meal and goes away after you eat, or it may come in the middle of the night when your stomach is empty
  • Losing weight
  • Loss of appetite
  • Pain while eating
  • Nausea
  • Vomiting

Diagnosis
Your doctor will ask about your symptoms and medical history. A physical exam may be done. Other tests may include:
  • Biopsy —removal of a sample of tissue for testing
  • Blood tests
  • Endoscopy —a thin, lighted tube inserted down the throat to examine parts of the body
  • Upper gastrointestinal (GI) X-ray —a series of x-rays of the upper digestive system taken after drinking a barium solution (also called a barium swallow)
  • Breath tests

Treatment
Talk with your doctor about the best plan for you. Some ulcers will heal if you avoid caffeine, NSAIDs, alcohol, and tobacco. Other treatment options include:

Medications
Treatment with medications focuses on:
  • Stopping your stomach from making acids
  • Killing the bacteria that is causing your ulcer

Medications used to treat gastric ulcers include:
  • Proton pump inhibitors
  • Histamine receptor blockers
  • Antibiotics
Antacids may also help reduce pain and heal ulcers.

Surgery
If ulcers do not heal with medications, surgery may be needed. Surgery can remove the ulcers and/or reduce the amount of acid your stomach makes.

If you are diagnosed with a gastric ulcer, follow your doctor's instructions .

Prevention
Steps you can take to prevent gastric ulcers include:
  • Stop using NSAIDs. You can talk with your doctor about alternatives
  • Do not smoke.
  • Do not drink alcohol.




RESOURCES:
American College of Gastroenterology

National Digestive Diseases Information Clearinghouse

CANADIAN RESOURCES:
Canadian Association of Gastroenterology


References:
DynaMed Editorial Team. Gastric peptic ulcer disease. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Updated July 9, 2010. Accessed November 5, 2010.

Helicobacter pylori and peptic ulcer disease. US Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/ulcer/history.htm . Accessed July 30, 2007.

Mayo Clinic. Peptic ulcer. Mayo Clinic website. Available at: http://www.mayoclinic.com/health/peptic-ulcer/DS00242 . Updated January 6, 2009. Accessed November 5, 2010.

Last Reviewed September 2011