Sulfasalazine
The following information is an educational aid only. It is not intended as a medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

Sulfasalazine
(sul fa SAL a zeen)

U.S. Brand Names
Azulfidine®; Azulfidine® EN-tabs®; Sulfazine; Sulfazine EC

Canadian Brand Names
Alti-Sulfasalazine; Salazopyrin En-Tabs®; Salazopyrin®

Mexican Brand Names
Azulfidina

Pharmacologic Category
5-Aminosalicylic Acid Derivative

Reasons not to take this medicine
• Do not give this medicine to a child younger than 2 years of age.

• If you have an allergy to sulfasalazine or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have a sulfonamide (“sulfa”) allergy, talk with healthcare provider.

• If you have any of the following conditions: Intestinal blockage, porphyria, or urinary tract blockage.

What is this medicine used for?
• This medicine is used to treat arthritis.

• This medicine is used to treat ulcerative colitis.

How does it work?
• Sulfasalazine reduces irritation and inflammation.

How is it best taken?
• Take this medicine with a full glass of water.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

• Swallow enteric-coated tablet whole. Do not chew, break, or crush.

What do I do if I miss a dose? (does not apply to patients in the hospital)
• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

What are the precautions when taking this medicine?
• If you are taking a blood thinner, you will require more frequent monitoring.

• Do not take antacids, iron, or folic acid within 4 hours of this medicine.

• This medicine may change the color of urine, sweat, and tears to yellow or orange color.

• This medicine may stain contact lenses.

• Protect clothing from staining.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.

• Be careful if you have G6PD deficiency. Anemia may occur.

• Sperm counts and motility can be decreased. This is reversible within 2 months after the medicine is stopped.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?
• Headache.

• Belly pain or heartburn.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Sunburn.

What should I monitor?
• Change in condition being treated. Is it better, worse, or about the same?

• Follow up with healthcare provider.

Reasons to call healthcare provider immediately
• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• If you see tablet bits in the stool.

• Severe belly pain or bloody diarrhea.

• Any rash.

• No improvement in condition or feeling worse.

How should I store this medicine?
• Store at room temperature.

• Protect from light.

• Protect from moisture. Do not store in a bathroom or kitchen.

General statements
• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2006-10-13 15:48:25.0

Modified: 2009-02-19 14:55:25.0

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