Endocarditis
En Español (Spanish Version)

Definition
The endocardium is the inner lining of the heart muscle. Endocarditis is an infection of this lining and the heart valves.

Causes
Causes include:
  • Bacterial infection (most common cause)
  • Viral or fungal infection
  • Medical conditions that result in blood clotting too easily (causes a noninfectious form)

Bacterial Endocarditis

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Risk Factors
Factors that increase your chance of endocarditis include:

Symptoms
Symptoms include:
  • Fever, chills
  • Weakness, low energy
  • Sweatiness, especially at night
  • Shortness of breath
  • Cough
  • Loss of appetite, weight loss
  • Chest pain
  • Abdominal pain
  • Nausea and vomiting
  • Painful red bumps on the fingers and toes
  • Purple dots on the whites of the eyes, under the fingernails, and over the collarbone
  • Painful red patches on the fingers, palms, and soles

Diagnosis
The doctor will ask about your symptoms and medical history. A physical exam will be done. The doctor will check your heart for unusual heart sounds. These are called heart murmurs .

Tests include:
  • Blood tests—to check for infection
  • Echocardiogram —uses high-frequency sound waves (ultrasound) to examine the size, shape, and motion of the heart

Treatment
Treatment may include:
  • Antibiotics—given through your veins for up to 4-8 weeks
  • Surgery—to repair or replace the valve if it is severely damaged or has caused heart failure

Prevention
If you have a high risk of infection:
  • You may need to take antibiotics before certain dental or medical procedures.
  • Talk to your dentist or doctor before the procedure.

The American Heart Association guidelines recommend that preventive antibiotic therapy should be considered for individuals with the following cardiac conditions:
  • Various forms of congenital heart disease (heart defects)
  • Artificial heart valves
  • History of endocarditis
  • Heart transplant recipients who have developed valve disease

Avoiding illegal IV drugs will also decrease your risk of infection.




RESOURCES:
American Heart Association

Heart Information Network

CANADIAN RESOURCES:
Heart and Stroke Foundation of Canada

University of Ottawa Heart Institute

References:
Braunwald E, Zipes DP, Libby P, et al. Heart Disease: A Textbook of Cardiovascular Medicine. 6th ed. Philadelphia, PA: WB Saunders Company; 2001.

Cecil RL, Goldman L, Bennett JC. Cecil Textbook of Medicine. 21st ed. Philadelphia, PA: WB Saunders Company; 2000.

Conn HF, Rakel RE, Bope ET. Conn's Current Therapy 2001: latest approved methods of treatment for the practicing physician. 53rd ed. Philadelphia, PA: WB Saunders Company; 2001.

DynaMed's Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : Wilson W, Taubert KA, Gewitz M, et al. Prevention of infective endocarditis. Guidelines from the American Heart Association. Circulation. 2007 Apr 19. [Epub ahead of print]

Last Reviewed September 2011