• What is Maté Used for Today?
  • Dosage
  • Safety Issues
  • Interactions You Should Know About
  • References
En Español (Spanish Version)

Maté is an evergreen tree native to Argentina, Brazil, Paraguay, and Uruguay. The leaves and small stems of the tree are used to make a tea-like caffeinated beverage. Maté has traditionally been used to enhance alertness and mental function, and also to treat digestive problems.

What is Maté Used for Today?
Maté is widely advertised as a healthful beverage, said to provide all the presumed benefits of green tea, such as preventing cancer and heart disease. However, the basis for this claim is largely theoretical. Maté does contain antioxidant polyphenols similar to those in tea, but this by itself does not demonstrate that mate is health-promoting; numerous substances with strong antioxidant properties have failed to prove beneficial in double-blind , placebo-controlled studies. Even green tea itself has not yet been proven to offer any health benefits.

In the test tube, mate has shown effects that suggest possible value for reducing cancer risk. 1-3 However, these findings are far too preliminary to rely upon; in fact, there is stronger evidence that maté could under certain circumstances increase risk of cancer (see Safety Issues ).

Other proposed benefits of maté also largely lack foundation. One study found that an extract of mate could help slow glycation, a metabolic side effect of diabetes. 4 These findings have been used to claim that maté is healthful for people with diabetes . However, this study did not involve people with diabetes; it involved chemicals in a test tube. Tens of thousands of substances show benefits in the test tube that fail to translate into real life; it is greatly premature to claim that maté is helpful for people with diabetes based on these exceedingly preliminary findings.

Similarly weak evidence hints that maté might increase fat metabolism, 5 and on this basis maté has been proposed as a weight-loss agent . However, there are no published human studies of maté that show any weight loss benefit. One small double-blind, placebo-controlled study evaluated an herbal preparation containing maté combined with guarana(Link tonew article) and damiana . 6 The herbal mixture appeared to cause participants to feel full more quickly during a meal, and to continue to feel full for longer after the meal; this led to modest, short-term weight loss. However, it is not clear to what extent the maté in this product played a role.

Another study found that maté might increase bile flow and speed the action of the intestines 7 ; these reported effects, even if real, do not indicate any particular health benefit.

Although some maté proponents attempted for many years to maintain that maté does not contain caffeine (supposedly it contained a chemical called “mateine,” which, in fact, does not exist), maté does in fact contain caffeine. Depending on how it is brewed, maté tea contains somewhat more caffeine than black tea and slightly less caffeine than coffee. Based on this caffeine content, maté would be expected to enhance mental function and improve sports performance .

A typical dose of maté is 3–10 grams dried herb per cup. Concentrated extracts are also available. These should be taken according to label instructions.

Safety Issues
As a widely consumed beverage maté is generally assumed to be entirely safe. However, this may be an incorrect assumption. Numerous studies have found associations between high consumption of maté in South American and increased rates cancer of the esophagous, mouth, throat, and larynx. 8-10 It is widely stated that this increased risk is entirely due to the practice of drinking maté at very high temperatures. However, the underlying evidence is not so clear-cut. The data actually suggest that at least some of this increased risk is be due to the maté itself, rather than the temperature at which it is consumed. 10 In addition, maté consumption has also been associated with increased risk of kidney and lung cancer, which would not be expected to be influenced by beverage temperature. 11,12 Finally, there is some direct evidence that mate has carcinogenic effects. 13 Putting all this information together, it does appear that maté is at the very least slightly carcinogenic. However, so is charred hamburger; moderate use of maté is not likely to significantly increase cancer risk.

Other potential problems with maté relate to its caffeine content. Potential side effects of caffeine include heartburn, gastritis, insomnia, anxiety, and heart arrhythmias (benign palpitations or more serious disturbances of heart rhythm.) 14 All drug interactions that can occur with caffeine would be expected to occur with maté as well (see next section).

Maximum safe doses have not been established in pregnant or nursing women, young children, or people with severe liver or kidney disease.

Interactions You Should Know About
If you are taking:
  • MAO inhibitors : The caffeine in maté could cause dangerous drug interactions.
  • Stimulant drugs such as Ritalin: The stimulant effects of maté might be amplified.
  • Drugs to prevent heart arrhythmias or treat insomnia , heartburn , ulcers , or anxiety : The caffeine in maté might interfere with their action.

References Gonzalez de Mejia E, Song YS, Ramirez-Mares MV, et al. Effect of yerba mate ( Ilex paraguariensis ) tea on topoisomerase inhibition and oral carcinoma cell proliferation. J Agric Food Chem . 2005;53:1966–73. Ramirez-Mares MV, Chandra S, de Mejia EG, et al. In vitro chemopreventive activity of Camellia sinensis , Ilexparaguariensis and Ardisia compressa tea extracts and selected polyphenols. Mutat Res . 2004;554:53–65. Chandra S, De Mejia Gonzalez E. Polyphenolic compounds, antioxidant capacity, and quinone reductase activity of an aqueous extract of Ardisia compressa in comparison to mate ( Ilex paraguariensis ) and green ( Camelliasinensis ) teas. J Agric Food Chem . 2004;52:3583–9. Lunceford N, Gugliucci A. Ilex paraguariensis extracts inhibit AGE formation more efficiently than green tea. Fitoterapia . 2005 May 12 [Epub ahead of print] Martinet A, Hostettmann K, Schutz Y, et al. Thermogenic effects of commercially available plant preparations aimed at treating human obesity. Phytomedicine . 2000;6:231–8. Andersen T, Fogh J. Weight loss and delayed gastric emptying following a South American herbal preparation in overweight patients. J Hum Nutr Diet . 2001;14:243–50. Gorzalczany S, Filip R, Alonso MR, et al. Choleretic effect and intestinal propulsion of 'mate' ( Ilex paraguariensis ) and its substitutes or adulterants. J Ethnopharmacol . 2001;75:291–4. Goldenberg D, Lee J, Koch WM, et al. Habitual risk factors for head and neck cancer. Otolaryngol Head Neck Surg . 2004;131:986–93. Sewram V, De Stefani E, Brennan P, et al. Mate consumption and the risk of squamous cell esophageal cancer in Uruguay. Cancer Epidemiol Biomarkers Prev . 2003;12:508–13. Goldenberg D, Golz A, Joachims HZ, et al. The beverage mate: a risk factor for cancer of the head and neck. Head Neck . 2003;25:595–601. De Stefani E, Fierro L, Mendilaharsu M, et al. Meat intake, 'mate' drinking and renal cell cancer in Uruguay: a case-control study. Br J Cancer . 1998;78:1239–43. De Stefani E, Fierro L, Correa P, et al. Mate drinking and risk of lung cancer in males: a case-control study from Uruguay. Cancer Epidemiol Biomarkers Prev . 1996;5:515–9. Leitao AC, Braga RS. Mutagenic and genotoxic effects of mate ( Ilex paraguariensis ) in prokaryotic organisms. Braz J Med Biol Res . 1995;27:1517–5. Cannon ME, Cooke CT, McCarthy JS. Caffeine-induced cardiac arrhythmia: an unrecognised danger of healthfood products. Med J Aust . 2001;174:520–1.
Last Reviewed August 2013

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